1 Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany Institute of Biostatistics, Hannover Medical School, Hannover, Germany Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany Departments of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany Department of Clinical Chemistry, Hannover Medical School, Hannover, Germany Institute of Biostatistics, Hannover Medical School, Hannover, Germany Departments of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.