Variation in amphibian response to two formulations of glyphosate-based herbicides

Environ Toxicol Chem. 2014 Nov;33(11):2628-32. doi: 10.1002/etc.2723. Epub 2014 Sep 22.

Abstract

Variation in toxicity among formulations and species makes it difficult to extrapolate results to all species and all formulations of herbicides. The authors exposed larval wood frogs (Lithobates sylvaticus) from 4 populations to 2 glyphosate-based herbicides, Roundup Weed and Grass Control® and Roundup WeatherMax®. The 96-h median lethal concentration values for both formulations varied among the populations (Roundup Weed and Grass Control, 0.14 mg acid equivalents (a.e.)/L to 1.10 mg a.e./L; Roundup WeatherMax, 4.94 mg a.e./L to 8.26 mg a.e./L), demonstrating that toxicity varies among the formulations and that susceptibility may differ among populations.

Keywords: Amphibian; Aquatic toxicology; Glyphosate; Herbicide; Roundup; Variation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Glycine / analogs & derivatives*
  • Glycine / analysis
  • Glyphosate
  • Herbicides / analysis*
  • Larva / drug effects
  • Ontario
  • Ranidae / physiology*
  • Reproducibility of Results
  • Water Pollutants, Chemical / analysis
  • Water Purification

Substances

  • Herbicides
  • Water Pollutants, Chemical
  • Glycine