Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model

Ann Rheum Dis. 2014 Nov;73(11):2062-4. doi: 10.1136/annrheumdis-2014-205672. Epub 2014 Aug 18.

Authors

Fumiko Yano¹, Shinsuke Ohba², Yoko Hosaka³, Taku Saito³, Ung-Il Chung⁴

Affiliations

¹ Center for Disease Biology and Integrative Medicine, University of Tokyo, Tokyo, Japan.
² Department of Bioengineering, The University of Tokyo, Tokyo, Japan.
³ Sensory and Motor System Medicine, The University of Tokyo, Tokyo, Japan.
⁴ Center for Disease Biology and Integrative Medicine, University of Tokyo, Tokyo, Japan Department of Bioengineering, The University of Tokyo, Tokyo, Japan.

PMID: 25135252
DOI: 10.1136/annrheumdis-2014-205672

No abstract available

Keywords: Chondrocytes; Knee Osteoarthritis; Osteoarthritis.

Publication types

Letter

MeSH terms

Animals
Antirheumatic Agents / therapeutic use*
Arthritis, Experimental / drug therapy*
Disease Progression
Drug Evaluation, Preclinical / methods
Heterocyclic Compounds, 4 or More Rings / therapeutic use*
Male
Mice
Mice, Inbred C57BL
Osteoarthritis / drug therapy*

Substances

Antirheumatic Agents
Heterocyclic Compounds, 4 or More Rings
TD-198946