Is there an association between diabetic neuropathy and low vitamin D levels?

Curr Diab Rep. 2014 Oct;14(10):537. doi: 10.1007/s11892-014-0537-6.

Abstract

In the past few years, the effects of vitamin D that go beyond its relationship with bone metabolism have come into the focus of scientific attention. Research concerning diabetes and its complications has become a public health priority. An increasing number of reports link vitamin D deficiency to diabetes; however, so far, there has only been limited and contradictory data available on the correlation between diabetic peripheral neuropathy and vitamin D. Studies of people with type 2 diabetes confirmed the relationship between vitamin D deficiency and neuropathy incidence as well as the severity of the symptoms caused by neuropathy. The latest studies are also suggesting a relationship between the incidence of plantar ulcers and vitamin D deficiency.

Publication types

  • Review

MeSH terms

  • Bone Density
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetic Neuropathies / epidemiology*
  • Diabetic Neuropathies / etiology
  • Diabetic Neuropathies / metabolism
  • Diabetic Neuropathies / physiopathology
  • Humans
  • Incidence
  • Public Health
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Severity of Illness Index
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / epidemiology*
  • Vitamin D Deficiency / metabolism
  • Vitamin D Deficiency / physiopathology