[Soft tissue tumor near the joint: hibernoma]

Z Orthop Unfall. 2014 Aug;152(4):366-8. doi: 10.1055/s-0034-1382860. Epub 2014 Aug 21.
[Article in German]

Abstract

Joint associated tumors must undergo histological analysis, since not only inflammatory, but also benign and malign tumors exist in this location. We report a well circumscribed tumor, located in the elbow that histologically turned out to be a hibernoma. Complete surgical excision is the therapy of choice and recurrences are rare. To rule out liposarcoma with hibernoma like changes, fluorescence in-situ hybridisation has been performed and showed no MDM-2 amplification. Hibernomas are tumors of brown adipose tissue that may be localized next to joints.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / analysis
  • Diagnosis, Differential
  • Elbow Joint* / pathology
  • Female
  • Humans
  • In Situ Hybridization, Fluorescence
  • Lipoma / diagnosis*
  • Lipoma / pathology
  • Lipoma / surgery*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Proto-Oncogene Proteins c-mdm2 / analysis
  • Soft Tissue Neoplasms / diagnosis*
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery*

Substances

  • Biomarkers, Tumor
  • Proto-Oncogene Proteins c-mdm2