Service evaluation of selected risk factors for extended-spectrum beta-lactamase Escherichia coli urinary tract infections: a case-control study

J Hosp Infect. 2014 Oct;88(2):116-9. doi: 10.1016/j.jhin.2014.07.009. Epub 2014 Aug 1.

Abstract

In the context of the increasing incidence of extended-spectrum beta-lactamase (ESBL) Escherichia coli infection, this prospective frequency-matched case-control study aimed to identify risk factors that would provide information and guidance for local clinical practice. One hundred and twelve participants were recruited: 54 cases and 58 controls. Univariate analysis indicated that isolation of an ESBL-producing E. coli in the previous 12 months and diabetes were significantly associated with the outcome. This study demonstrates the utility of service evaluation studies for producing epidemiological information to inform clinical practice.

Keywords: Case–control; Escherichia coli; Extended-spectrum beta-lactamase; Urinary tract infection.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Diabetes Complications / microbiology*
  • Escherichia coli / enzymology*
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Proteins / metabolism
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / etiology
  • Urinary Tract Infections / microbiology*
  • beta-Lactamases / metabolism*

Substances

  • Escherichia coli Proteins
  • beta-Lactamases