Genomic characterization of a circovirus associated with fatal hemorrhagic enteritis in dog, Italy

PLoS One. 2014 Aug 22;9(8):e105909. doi: 10.1371/journal.pone.0105909. eCollection 2014.

Abstract

Dog circovirus (DogCV) was identified in an outbreak of enteritis in pups in Italy. The disease was observed in 6 young dachshunds pups of a litter from a breeding kennel and caused the death of 2 dogs. Upon full-genome analysis, the virus detected in one of the dead pups (strain Bari/411-13) was closely related to DogCVs that have been recently isolated in the USA. The present study, if corroborated by further reports, could represent a useful contribution to the knowledge of the pathogenic potential of DogCV and its association with enteritis in dogs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Circoviridae Infections / epidemiology
  • Circoviridae Infections / veterinary
  • Circoviridae Infections / virology*
  • Circovirus / genetics*
  • Circovirus / isolation & purification
  • Circovirus / pathogenicity
  • Disease Outbreaks
  • Dog Diseases / virology*
  • Dogs
  • Enteritis / mortality
  • Enteritis / veterinary*
  • Enteritis / virology
  • Genome, Viral*
  • Italy / epidemiology
  • Molecular Sequence Data
  • Phylogeny

Associated data

  • GENBANK/AF071878
  • GENBANK/AJ301633
  • GENBANK/AY424401
  • GENBANK/AY660574
  • GENBANK/DQ100076
  • GENBANK/DQ146997
  • GENBANK/DQ845074
  • GENBANK/EU056310
  • GENBANK/GQ404844
  • GENBANK/GQ404845
  • GENBANK/GQ404856
  • GENBANK/GQ404857
  • GENBANK/GU799606
  • GENBANK/HQ738643
  • GENBANK/JQ011378
  • GENBANK/JQ821392
  • GENBANK/KC241983
  • GENBANK/KC241984
  • GENBANK/KJ530972

Grants and funding

This work was supported by grants from the Italian Ministry of Health, Ricerca corrente 2009, project IZS VE 21/09 RC “Definizione di una procedura validata per la selezione di cani per programmi di Interventi Assistiti dagli Animali (IAA)”. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.