Abstract
The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of this influenza virus.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cells, Cultured
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Chick Embryo
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Chickens
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Dogs
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Genes, Viral
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Genome, Viral
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Humans
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Influenza A Virus, H10N8 Subtype / classification
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Influenza A Virus, H10N8 Subtype / genetics*
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Influenza A Virus, H10N8 Subtype / isolation & purification
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Influenza, Human / virology
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Madin Darby Canine Kidney Cells
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Molecular Sequence Data
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Mutation*
Associated data
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GENBANK/KJ406531
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GENBANK/KJ406532
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GENBANK/KJ406533
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