Management of a major atlanto-axial instability secondary to a lytic lesion of C2

Eur Spine J. 2015 Jan;24(1):180-4. doi: 10.1007/s00586-014-3513-6. Epub 2014 Aug 26.

Abstract

Introduction: Management of C1-C2 instability is very challenging, especially when tumoral lesions are involved.

Case report: We present the case of a 65-year-old male, with a recently discovered small cell lung carcinoma, presenting progressive tetraparesis due to a secondary lesion involving the body of C2 with complete collapse of its anterior part and major C1-C2 instability in all planes. The patient underwent a reconstructive surgery of the upper cervical spine during two sessions. First, an emergency surgery was done by a high anterior cervical approach, where reconstruction of the body of C2 was done by an original technique using a C3 body to odontoid long screw with bone cement filling around the screw at the level of C2, and an anterior buttress plate put from C2 to C4. A posterior surgery was performed after 48 h to stabilize the spine posteriorly with C1 to C5 instrumentation. The patient recovered from his neurological symptoms, and underwent complementary adjuvant radiotherapy with chemotherapy later on.

Conclusion: Literature is sparse on the treatment of major C1-C2 instability, especially when a secondary lesion is involved, the current case shows a successful treatment strategy with an original technique that was never described before in the literature. The patient was pain free at 1 year follow-up with a stable construct.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Atlanto-Axial Joint / surgery*
  • Bone Plates
  • Bone Screws
  • Cervical Vertebrae / surgery*
  • Humans
  • Joint Instability / etiology
  • Joint Instability / surgery*
  • Lung Neoplasms / pathology
  • Male
  • Quadriplegia / etiology
  • Quadriplegia / surgery
  • Small Cell Lung Carcinoma / pathology
  • Small Cell Lung Carcinoma / secondary
  • Small Cell Lung Carcinoma / surgery
  • Spinal Neoplasms / complications*
  • Spinal Neoplasms / secondary
  • Spinal Neoplasms / surgery*