A lack of understanding about the distinction between incontinence-associated dermatitis and pressure sores leads to inadequate treatment and therefore a higher incidence of pressure sores. Pressure relief may not be adequately carried out due to concentration exclusively on treatment of incontinence. In this article we will discuss the multifactorial approach, based on 2 patient cases. In order to prevent pressure sores, the cause of incontinence has to be investigated and treated if possible. Appropriate pressure relief must be carried out, in addition to adequate skin care.