Family history of education predicts eating disorders across multiple generations among 2 million Swedish males and females

PLoS One. 2014 Aug 27;9(8):e106475. doi: 10.1371/journal.pone.0106475. eCollection 2014.

Abstract

Purpose: To investigate which facets of parent and grandparent socio-economic position (SEP) are associated with eating disorders (ED), and how this varies by ED subtype and over time.

Methods: Total-population cohort study of 1,040,165 females and 1,098,188 males born 1973-1998 in Sweden, and followed for inpatient or outpatient ED diagnoses until 2010. Proportional hazards models estimated associations with parental education, income and social class, and with grandparental education and income.

Results: 15,747 females and 1051 males in our sample received an ED diagnosis, with rates increasing in both sexes over time. ED incidence in females was independently predicted by greater educational level among the father, mother and maternal grandparents, but parent social class and parental income showed little or no independent effect. The associations with education were equally strong for anorexia nervosa, bulimia nervosa and ED not-otherwise-specified, and had increased over time. Among males, an apparently similar pattern was seen with respect to anorexia nervosa, but non-anorexia ED showed no association with parental education and an inverse association with parental income.

Conclusions: Family history of education predicts ED in gender- and disorder-specific ways, and in females the effect is observed across multiple generations. Particularly given that these effects may have grown stronger in more recent cohorts, these findings highlight the need for further research to clarify the underlying mechanisms and identify promising targets for prevention. Speculatively, one such mechanism may involve greater internal and external demands for academic success in highly educated families.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anorexia Nervosa / economics
  • Anorexia Nervosa / epidemiology*
  • Anorexia Nervosa / physiopathology
  • Anorexia Nervosa / psychology
  • Bulimia Nervosa / economics
  • Bulimia Nervosa / epidemiology*
  • Bulimia Nervosa / physiopathology
  • Bulimia Nervosa / psychology
  • Educational Status
  • Female
  • Humans
  • Incidence
  • Income / statistics & numerical data
  • Male
  • Parents / education*
  • Parents / psychology
  • Risk Factors
  • Social Class
  • Sweden / epidemiology

Grants and funding

This work was supported by the Swedish Research Council (grant numbers 2008-7483, 2009-3146) and the Swedish Council for Health, Working Life and Social Research (grant numbers 2006-1518 and 2013-1084). The latter organisation also funds IK. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.