Abstract
Polycomb/Trithorax response elements (PRE/TREs) are genetic elements that can stably silence or activate genes. A new study describes how long noncoding RNAs (lncRNAs) transcribed from opposite strands of the Drosophila melanogaster vestigial PRE/TRE throw the switch between these two opposing epigenetic states.
MeSH terms
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Animals
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Chromosomal Proteins, Non-Histone / genetics*
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Drosophila Proteins / genetics*
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Genes, Switch*
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Polycomb-Group Proteins / genetics*
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RNA, Untranslated*
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Response Elements*
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Transcription, Genetic*
Substances
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Chromosomal Proteins, Non-Histone
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Drosophila Proteins
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Polycomb-Group Proteins
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RNA, Untranslated
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trx protein, Drosophila