Mycobacterium tuberculosis, a globally significant pathogen, results in active or latent tuberculosis. The granuloma is the characteristic lesion that offers insight into host-pathogen interactions in these distinct states. Microdissection provides a way to isolate and consequently investigate specific tissue sections. We review various techniques available and in use.
Keywords: Mycobacterium tuberculosis; dissection; granuloma; mesodissection; non-human primate.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.