Proteinuria and haematuria are frequently present in patients with lung cancer

Nephrol Dial Transplant. 1989;4(11):947-50. doi: 10.1093/ndt/4.11.947.

Abstract

The aim of the study was to ascertain whether there is an increased occurrence of proteinuria and/or haematuria among lung cancer patients. As a control group we selected patients with bronchial asthma treated at the same hospital and during the same period as the lung cancer patients. The study comprised a retrospective part, where observations were made at two hospitals on 166 and 284 lung cancer patients. Proteinuria was observed in 9% and 13% and haematuria in 5% and 9% of these patients. The prevalences were significantly greater than among the asthmatic patients. This result prompted a prospective case-control study involving 150 consecutive patients with lung cancer and asthma, respectively. Twelve patients in the cancer group and one asthmatic patient had a daily urine protein excretion exceeding 100 mg (P less than 0.004); haematuria was noted in 14 and one, respectively (P less than 0.002). We conclude that the occurrence of proteinuria and haematuria is unexpectedly increased among patients with lung cancer.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Asthma / complications
  • Case-Control Studies
  • Female
  • Hematuria / epidemiology
  • Hematuria / etiology*
  • Humans
  • Lung Neoplasms / complications*
  • Male
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Proteinuria / epidemiology
  • Proteinuria / etiology*
  • Retrospective Studies