Isolation of protein-associated circular DNA from healthy cattle serum

Mathis Funk; Karin Gunst; Vincent Lucansky; Hermann Müller; Harald Zur Hausen; Ethel-Michele de Villiers

doi:10.1128/genomeA.00846-14

Isolation of protein-associated circular DNA from healthy cattle serum

Genome Announc. 2014 Aug 28;2(4):e00846-14. doi: 10.1128/genomeA.00846-14.

Authors

Mathis Funk¹, Karin Gunst¹, Vincent Lucansky¹, Hermann Müller², Harald Zur Hausen¹, Ethel-Michele de Villiers³

Affiliations

¹ Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
² Institute for Virology, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
³ Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, Germany [email protected].

Abstract

Three replication-competent single-stranded DNA molecules sharing nucleotide similarity to transmissible spongiform encephalopathy (TSE)-associated isolate Sphinx 2.36 were isolated from healthy bovine serum.