Diversified bioactivities of four types of naturally occurring quinochalcones

Fitoterapia. 2014 Dec:99:7-20. doi: 10.1016/j.fitote.2014.08.017. Epub 2014 Aug 27.

Abstract

Quinochalcones, quinone-containing chalcones, belong to the flavonoid family and have attracted increasing popularity in Western countries in the last decade due to their pharmacological activities. This review describes four types of naturally occurring quinochalcones and summarizes their different pharmacological activities, including anti-cerebral ischemia, anti-tumor, and anti-infection activities. In addition, the pharmacological activities and relevant structure-activity relationships of synthetic quinochalcones are also reviewed.

Keywords: Anti-cerebral ischemia; Anti-infection; Anti-tumor; Quinochalcone; Structure–activity relationship.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Antineoplastic Agents / pharmacology
  • Antioxidants / pharmacology
  • Chalcones / classification
  • Chalcones / pharmacology*
  • Molecular Structure
  • Neuroprotective Agents / pharmacology
  • Quinones / classification
  • Quinones / pharmacology*
  • Structure-Activity Relationship

Substances

  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Antioxidants
  • Chalcones
  • Neuroprotective Agents
  • Quinones