Recurrent right atrial thrombosis due to Behçet disease

Can J Cardiol. 2014 Oct;30(10):1250.e1-3. doi: 10.1016/j.cjca.2014.05.011. Epub 2014 May 21.

Abstract

Behçet disease is a rare condition sometimes associated with chronic cardiac inflammation followed by myocardial dysfunction and vascular inflammation. We report a case of recurrent right atrial thrombus due to Behçet disease despite continued anticoagulation therapy. The thrombus disappeared after the initiation of immunosuppressive therapy. To avoid a progression to thrombus or cardiac dysfunction in this recurrent case, the early identification of cardiac involvement of Behçet disease using echocardiography and/or cardiac magnetic resonance imaging might be important. Combined immunosuppressive therapy with prednisone and cyclophosphamide might be needed to treat recurrent thrombosis due to Behçet disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anticoagulants / therapeutic use
  • Azathioprine / therapeutic use
  • Behcet Syndrome / complications*
  • Behcet Syndrome / physiopathology
  • Disease Progression
  • Heart Atria
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / etiology*
  • Heart Diseases / physiopathology
  • Heart Diseases / prevention & control
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Inflammation
  • Male
  • Middle Aged
  • Myocardium / pathology
  • Prednisone / therapeutic use
  • Recurrence
  • Stroke Volume
  • Thrombosis / diagnostic imaging
  • Thrombosis / etiology*
  • Thrombosis / physiopathology
  • Thrombosis / prevention & control
  • Ultrasonography

Substances

  • Anticoagulants
  • Immunosuppressive Agents
  • Azathioprine
  • Prednisone