A total body hyperthermia animal model for pharmacological studies

G de Feo; R Lisciani; A Capezzone de Joannon; G Mazzanti; L Tolu; S Pace

A total body hyperthermia animal model for pharmacological studies

In Vivo. 1989 Sep-Oct;3(5):295-9.

Authors

G de Feo¹, R Lisciani, A Capezzone de Joannon, G Mazzanti, L Tolu, S Pace

Affiliation

¹ Institute of Pharmacology and Pharmacognosy, University of Rome La Sapienza, Italy.

PMID: 2519868

Abstract

Toxic side effects are the main drawback in localized and total body hyperthermia for the treatment of tumours. This paper reports a total body hyperthermia animal model which may be used as an experimental tool in the search for conditions or drugs capable of inhibiting the toxic effects of hyperthermia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Body Temperature*
Death
Female
Hyperthermia, Induced*
Male
Mice
Mice, Inbred Strains
Models, Biological
Sex Characteristics