Hubei Provincial Hospital of Traditional Chinese Medicine established research outpatient clinics to contribute to the major disease-entity research conducted by the National Traditional Chinese Medicine Clinical Research Base and to the construction of the National Traditional Chinese Medicine Treatment and Clinical Research Information Sharing System. With a view of developing a "real-world traditional Chinese medicine clinical research paradigm," these clinics explored the mode of constructing research outpatient clinics from the aspects of clinical research, health management, and characteristics diagnosis and treatment.