Establishment of an orthotopic model of pancreatic cancer to evaluate the antitumor effects of irinotecan through the biomarker carbohydrate antigen 19-9 in mice

Pancreas. 2014 Oct;43(7):1126-8. doi: 10.1097/MPA.0000000000000183.

Authors

Lin Li¹, Grace G L Yue, Kwok Pui Fung, Ping Chung Leung, Clara B S Lau, Po Sing Leung

Affiliation

¹ School of Biomedical Sciences Institute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Hong Kong, China Institute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Hong Kong, China School of Biomedical Sciences Institute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Hong Kong, China Institute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Hong Kong, China School of Biomedical Sciences The Chinese University of Hong Kong Hong Kong, China [email protected].

PMID: 25207664
DOI: 10.1097/MPA.0000000000000183

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adenocarcinoma / blood
Adenocarcinoma / drug therapy*
Adenocarcinoma / pathology
Animals
Antigens, Neoplasm / blood*
Antineoplastic Agents, Alkylating / therapeutic use*
Biomarkers, Tumor / blood*
CA-19-9 Antigen / blood*
Camptothecin / analogs & derivatives*
Camptothecin / therapeutic use
Cell Line, Tumor
Humans
Irinotecan
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Transplantation
Pancreatic Neoplasms / blood
Pancreatic Neoplasms / drug therapy*
Pancreatic Neoplasms / pathology
Random Allocation
Xenograft Model Antitumor Assays*

Substances

Antigens, Neoplasm
Antineoplastic Agents, Alkylating
Biomarkers, Tumor
CA-19-9 Antigen
Irinotecan
Camptothecin