A partial pathway- and network-based transformation reveals the synergistic mechanism of JA and UA against cerebral ischemia-reperfusion injury

Protein Cell. 2014 Nov;5(11):873-7. doi: 10.1007/s13238-014-0098-0.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / metabolism
  • Brain / pathology
  • Brain Ischemia / complications
  • Drug Synergism
  • Gene Regulatory Networks / drug effects*
  • Gene Regulatory Networks / genetics
  • Iridoids / pharmacology*
  • Linear Models
  • Male
  • Mice
  • Models, Genetic
  • Oligonucleotide Array Sequence Analysis
  • Reperfusion Injury / drug therapy*
  • Reperfusion Injury / etiology
  • Reperfusion Injury / genetics
  • Signal Transduction / drug effects*
  • Signal Transduction / genetics
  • Transcriptome / drug effects
  • Transcriptome / genetics
  • Ursodeoxycholic Acid / pharmacology*

Substances

  • Iridoids
  • geniposide
  • Ursodeoxycholic Acid