Overdosage of methylparaben induces cellular senescence in vitro and in vivo

J Invest Dermatol. 2015 Feb;135(2):609-612. doi: 10.1038/jid.2014.405. Epub 2014 Sep 17.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cellular Senescence / drug effects*
  • Drug Overdose
  • Glutathione Peroxidase / genetics
  • Glutathione Peroxidase GPX1
  • Humans
  • In Vitro Techniques
  • Parabens / poisoning*
  • Preservatives, Pharmaceutical / poisoning*
  • Reactive Oxygen Species / metabolism
  • Receptors, Glucocorticoid / physiology
  • Superoxide Dismutase / genetics
  • Superoxide Dismutase-1

Substances

  • Parabens
  • Preservatives, Pharmaceutical
  • Reactive Oxygen Species
  • Receptors, Glucocorticoid
  • SOD1 protein, human
  • glucocorticoid receptor alpha
  • methylparaben
  • Glutathione Peroxidase
  • Superoxide Dismutase
  • Superoxide Dismutase-1
  • Glutathione Peroxidase GPX1
  • GPX1 protein, human