Abstract
We describe an exceptional case of life-threatening group A Escherichia coli-induced purpura fulminans. Genotyping of common polymorphisms in genes involved in innate immunity or coagulation did not reveal known susceptibility to such a manifestation. Genetic analysis of the strain revealed an unusual conserved virulence plasmidic region, pointing out its potential virulence.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.
MeSH terms
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DNA, Bacterial / genetics
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Escherichia coli / classification*
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Escherichia coli / growth & development
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Escherichia coli / isolation & purification*
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Escherichia coli Infections / complications*
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Escherichia coli Infections / microbiology*
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Escherichia coli Infections / pathology
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Female
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Genotype
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Histocytochemistry
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Humans
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Microscopy
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Middle Aged
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Plasmids
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Purpura Fulminans / diagnosis*
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Purpura Fulminans / microbiology*
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Purpura Fulminans / pathology
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Virulence
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Virulence Factors / genetics
Substances
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DNA, Bacterial
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Virulence Factors