The inside track: privileged neural communication through axon-carrying dendrites

Patrick Kaifosh; Attila Losonczy

doi:10.1016/j.neuron.2014.09.003

The inside track: privileged neural communication through axon-carrying dendrites

Neuron. 2014 Sep 17;83(6):1231-4. doi: 10.1016/j.neuron.2014.09.003.

Authors

Patrick Kaifosh¹, Attila Losonczy²

Affiliations

¹ Department of Neuroscience, Columbia University, New York, NY 10032, USA; Doctoral Program in Neurobiology and Behavior, Columbia University, New York, NY 10032, USA. Electronic address: [email protected].
² Department of Neuroscience, Columbia University, New York, NY 10032, USA; Kavli Institute for Brain Science, Columbia University, New York, NY 10032, USA. Electronic address: [email protected].

PMID: 25233301
DOI: 10.1016/j.neuron.2014.09.003

Abstract

Whether morphology tailors functional properties of pyramidal neurons is not completely understood. In this issue of Neuron, Thome et al. (2014) show that, in hippocampal pyramidal neurons, axons frequently originate from basal dendrites rather than the soma, constituting a "privileged" channel for synaptic inputs located in these axon-carrying dendrites.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Axons / physiology*
Dendrites / physiology*
Female
Hippocampus / physiology*
Male
Pyramidal Cells / physiology*
Synaptic Transmission / physiology*

Abstract

Publication types

MeSH terms

Grants and funding