Abstract
The influenza A virus (IAV) subtypes H1N1, H3N2 and H1N2 are the most prevalent subtypes in swine in Italy. Reassortant influenza A viruses subtypes in swine appeared in European pig population. In particular reassortant viruses carrying genome segment from the pandemic H1N1 (H1N1pdm) are reported in many European countries, including Italy. In a 1000 sows farrow-to feeder farm, in Northern Italy, we isolated 10 IAVs from recurrent episodes of respiratory disease in 45-70 days-old pigs from September 2012 to June 2013. The antigenic and genetic characterization of the swine IAV isolates showed the contemporary circulation of H1N1 avian-like and H1N1pdm strains in the first outbreak. The analysis of the viruses isolated subsequently showed the circulation of H1N1pdm IAV and then the establishment of a new previously undescribed H1N1 reassortant strain with a pandemic derived hemagglutinin gene and all the other seven segments of swine H1N1 avian-like lineage.
Keywords:
H1N1; Reassortant; Swine influenza A virus.
Copyright © 2014 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Base Sequence
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Epidemiological Monitoring / veterinary*
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Influenza A Virus, H1N1 Subtype / genetics*
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Italy / epidemiology
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Molecular Sequence Data
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Orthomyxoviridae Infections / epidemiology
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Orthomyxoviridae Infections / veterinary*
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Real-Time Polymerase Chain Reaction / veterinary
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Reassortant Viruses / genetics*
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Respiration Disorders / epidemiology
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Respiration Disorders / veterinary*
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Respiration Disorders / virology
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Sequence Analysis, DNA / veterinary
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Swine
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Swine Diseases / epidemiology*
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Swine Diseases / virology*
Associated data
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GENBANK/KF500932
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