Update on multiple sclerosis treatments

Swiss Med Wkly. 2014 Sep 23:144:w14012. doi: 10.4414/smw.2014.14012. eCollection 2014.

Abstract

Relapsing-remitting multiple sclerosis (RRMS) management has dramatically changed over the past decade. New drugs have arrived on the market, allowing for more individualised treatment selection. However, this diversity has increased the complexity of RRMS patient follow-up. In this review, we provide summarised information about treatment efficacy, potential side-effects, follow-up recommendations, vaccinations, and pregnancy safety issues for all currently available disease modifying therapies and those awaiting approval.

Publication types

  • Review

MeSH terms

  • Alemtuzumab
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Crotonates / therapeutic use
  • Daclizumab
  • Dimethyl Fumarate
  • Fingolimod Hydrochloride
  • Fumarates / therapeutic use
  • Humans
  • Hydroxybutyrates
  • Immunoglobulin G / therapeutic use
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Interferon-beta / therapeutic use
  • Multiple Sclerosis, Relapsing-Remitting / drug therapy*
  • Natalizumab
  • Nitriles
  • Propylene Glycols / therapeutic use
  • Sphingosine / analogs & derivatives
  • Sphingosine / therapeutic use
  • Toluidines / therapeutic use

Substances

  • Antibodies, Monoclonal, Humanized
  • Crotonates
  • Fumarates
  • Hydroxybutyrates
  • Immunoglobulin G
  • Immunosuppressive Agents
  • Natalizumab
  • Nitriles
  • Propylene Glycols
  • Toluidines
  • teriflunomide
  • Alemtuzumab
  • Interferon-beta
  • ocrelizumab
  • Daclizumab
  • Dimethyl Fumarate
  • Fingolimod Hydrochloride
  • Sphingosine