Intralesional cryosurgery to treat keloid scars: results from a retrospective study

Dermatology. 2014;229(3):263-70. doi: 10.1159/000365392. Epub 2014 Sep 20.

Abstract

Background: A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars.

Objective: To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Feedback from patients on pain, pruritus and aesthetic discomfort was recorded before and after treatment.

Methods: A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013. The efficacy of this treatment was evaluated by measuring the reduction in scar surface.

Results: Scar surface was reduced by an average of 58.5% after intralesional cryosurgery treatment for all scars (average pre-operative keloid scar surface: 874.6 ± 954.1 mm2; average post-operative keloid scar surface: 505.8 ± 1,024.7 mm2; p = 0.002). Pain and aesthetic discomfort were significantly decreased after treatment in all patients (p = 0.008 and p = 0.012, respectively).

Conclusion: Our data suggest that intralesional cryosurgery is an effective treatment for keloids.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cicatrix / complications*
  • Cicatrix / physiopathology
  • Cryosurgery / methods*
  • Esthetics
  • Female
  • Follow-Up Studies
  • Humans
  • Keloid / etiology
  • Keloid / pathology*
  • Keloid / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Young Adult