Molecular epidemiology of and genetic susceptibility to esophageal cancer

Manisha Bajpai; Kiron M Das; Joel Lefferts; Mikhail Lisovsky; Hiroshi Mashimo; Wayne A Phillips; Amitabh Srivastava; Henry To

doi:10.1111/nyas.12517

Molecular epidemiology of and genetic susceptibility to esophageal cancer

Ann N Y Acad Sci. 2014 Sep:1325:40-8. doi: 10.1111/nyas.12517.

Authors

Manisha Bajpai¹, Kiron M Das, Joel Lefferts, Mikhail Lisovsky, Hiroshi Mashimo, Wayne A Phillips, Amitabh Srivastava, Henry To

Affiliation

¹ Division of GI/Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

PMID: 25266013
DOI: 10.1111/nyas.12517

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on clonal evolution in Barrett's carcinogenesis; biomarkers for early detection of esophageal cancer; the role of the methylguanine methyl transferase biomarker in the management of adenocarcinoma; and the discovery of high-risk genes in families.

Keywords: Barrett's epithelium carcinogenesis; MGMT; OESO; biomarkers; esophageal adenocarcinoma; esophageal cancer.

Publication types

Congress

MeSH terms

Animals
Barrett Esophagus / diagnosis
Barrett Esophagus / epidemiology
Barrett Esophagus / genetics
Biomarkers, Tumor / genetics
Cell Transformation, Neoplastic / genetics
Cell Transformation, Neoplastic / pathology
Esophageal Neoplasms / diagnosis
Esophageal Neoplasms / epidemiology*
Esophageal Neoplasms / genetics*
Genetic Predisposition to Disease / epidemiology*
Genetic Predisposition to Disease / genetics*
Humans
Molecular Epidemiology
Paris

Substances

Biomarkers, Tumor