Transvaginal surgical management of cesarean scar pregnancy: analysis of 49 cases from one tertiary care center

Eur J Obstet Gynecol Reprod Biol. 2014 Nov:182:102-6. doi: 10.1016/j.ejogrb.2014.09.017. Epub 2014 Sep 16.

Abstract

Objective: To investigate the safety and effectiveness of transvaginal surgical management of cesarean scar pregnancy (CSP).

Study design: Retrospective analysis of 49 CSP patients who received transvaginal surgery in our hospital between December 2009 and April 2013. Patients were divided into two groups. Group A (30 patients) was defined as patients who had not received any treatment before transvaginal surgical management. Group B (19 patients) referred to patients who had received any previous treatment. Preoperative, intraoperative and postoperative data of both groups were collected and analyzed retrospectively.

Results: Preoperative serum β-hCG level, preoperative hemoglobin level and average serum β-hCG resolution time of group A and group B were 53,458.50 (36,382.00-94,100.50) versus 9779.00 (932.50-29623.00)U/l, 123.87±10.95 versus 109.94±16.05 g/l and 3.55±1.81 versus 1.83±1.15 weeks (P<0.05). Vaginal bleeding and gestational age in group A were significantly lower than in group B, 2.5 (0.50-11.00) versus 15.00 (3.50-31.50) days and 52.50 (46.50-56.70) versus 60.00 (48.00-90.00) days, respectively (P<0.05). The operative time, estimated blood loss, postoperative hospital stay, hospitalization expenses and menstruation recovery time of group A and group B were 56.61±24.40 versus 67.56±43.52 min, 45.65±27.83 versus 76.67±50.87 ml, 5.10±2.89 versus 5.33±3.99 days, 9001.94±1848.37 versus 11,032.33±5534.14 RMB and 1.16±0.47 versus 1.26±0.63 month respectively, which were similar between the two groups (P>0.05). The intraoperative complication rate in group A was significantly lower than group B, 0 (0/30) versus 21.05% (4/19) (P<0.05). The postoperative complication rate and total complication rate in group A and group B were 10.00% (3/30) versus 21.05% (4/19) and 10.00% (3/30) versus 31.58% (6/19) (P>0.05), respectively.

Conclusion: Transvaginal surgery is an effective and relatively safe treatment option for CSP patients.

Keywords: Cesarean scar pregnancy; Pregnancy outcome; Transvaginal surgery.

MeSH terms

  • Adult
  • Blood Loss, Surgical
  • Cesarean Section / adverse effects*
  • Chorionic Gonadotropin, beta Subunit, Human / blood
  • Cicatrix / complications*
  • Female
  • Gestational Age
  • Hemoglobins / metabolism
  • Humans
  • Length of Stay / economics
  • Menstruation
  • Operative Time
  • Pregnancy
  • Pregnancy, Ectopic / blood
  • Pregnancy, Ectopic / etiology
  • Pregnancy, Ectopic / surgery*
  • Recovery of Function
  • Retrospective Studies
  • Tertiary Care Centers
  • Uterine Hemorrhage / etiology
  • Uterine Hemorrhage / surgery
  • Vagina

Substances

  • Chorionic Gonadotropin, beta Subunit, Human
  • Hemoglobins