Oxytocin: taking the heat

Glob Health Sci Pract. 2014 Aug 31;2(3):259-60. doi: 10.9745/GHSP-D-14-00102. eCollection 2014 Aug.

Abstract

Oxytocin-in-Uniject satisfied the standards of its temperature-time indicator (TTI) in severe home storage conditions, although that required resupply every 30 days-a logistically onerous programmatic standard. Possible advances include: (1) incorporating TTIs with packaged batches of less expensive and more widely used conventional vials of oxytocin; (2) using TTIs calibrated more closely to the actual temperature sensitivity of oxytocin; and (3) researching whether a lower dose of oxytocin would be equally efficacious in preventing postpartum hemorrhage.

MeSH terms

  • Drug Stability*
  • Drug Storage / methods
  • Female
  • Humans
  • Oxytocics / chemistry
  • Oxytocics / therapeutic use*
  • Oxytocin / chemistry
  • Oxytocin / therapeutic use*
  • Postpartum Hemorrhage / drug therapy
  • Postpartum Hemorrhage / prevention & control*
  • Pregnancy
  • Temperature*

Substances

  • Oxytocics
  • Oxytocin