Antioxidant neolignan and phenolic glucosides from the fruit of Euterpe oleracea

Fitoterapia. 2014 Dec:99:178-83. doi: 10.1016/j.fitote.2014.09.020. Epub 2014 Oct 7.

Abstract

Three new glucosides, namely, (-)-7R8S-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (1), (+)-7S8R-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (2) and 4-hydroxy-2-methoxyphenyl 1-O-[6-(hydrogen 3-hydroxy-3-methylpentanedioate)]-β-D-glucopyranoside (3), along with 6 known compounds were isolated from the fruit of Euterpe oleracea Mart. Their structures were elucidated based on spectroscopic analyses including NMR, HR-ESI-MS and CD. All the isolated compounds demonstrated significant antioxidant activity and 2 displayed moderate cytotoxicity against HL-60 cells.

Keywords: Antioxidant activity; Arecaceae; Açaí; Euterpe oleracea; Glucoside.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry
  • Euterpe / chemistry*
  • Fruit / chemistry*
  • Glucosides / chemistry*
  • HL-60 Cells
  • Humans
  • Lignans / chemistry*
  • Molecular Structure
  • Phenols / chemistry

Substances

  • Antioxidants
  • Glucosides
  • Lignans
  • Phenols