Reduction of myocardial damage and polymorphonuclear leukocyte accumulation following coronary artery occlusion and reperfusion by the thromboxane receptor antagonist BM 13.505

Prog Clin Biol Res. 1989:301:161-5.

Authors

D E Griswold¹, J W Egan, C Q Earl, L M Hillegass, P J Marshall, E F Smith 3rd

Affiliation

¹ Smith Kline and French Laboratories, Department of Immunology, King of Prussia, PA 19406.

PMID: 2529547

No abstract available

MeSH terms

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Animals
Coronary Disease / drug therapy
Coronary Disease / pathology
Male
Myocardial Infarction / pathology
Myocardial Infarction / prevention & control
Myocardial Reperfusion Injury / pathology
Myocardial Reperfusion Injury / prevention & control*
Neutrophils / drug effects
Neutrophils / pathology
Phenylacetates / pharmacology*
Prostaglandin Endoperoxides, Synthetic / antagonists & inhibitors
Rats
Rats, Inbred Strains
Receptors, Prostaglandin
Receptors, Thromboxane
Sulfonamides / pharmacology*

Substances

Phenylacetates
Prostaglandin Endoperoxides, Synthetic
Receptors, Prostaglandin
Receptors, Thromboxane
Sulfonamides
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
daltroban