R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade, combined in one molecule

Prog Clin Biol Res. 1989:301:567-72.

Authors

F De Clerck¹, J Beetens, D de Chaffoy de Courcelles, E Vercammen, E Freyne, P A Janssen

Affiliation

¹ Department of Haematol, Janssen Research Foundation, Beerse, Belgium.

PMID: 2529556

No abstract available

MeSH terms

Animals
Arachidonic Acid
Arachidonic Acids / blood
Blood Platelets / drug effects
Blood Platelets / metabolism
Humans
In Vitro Techniques
Pentanoic Acids / pharmacology*
Platelet Aggregation / drug effects
Prostaglandin Endoperoxides / blood
Pyridines / pharmacology*
Rats
Receptors, Prostaglandin / metabolism
Receptors, Thromboxane
Thromboxane A2 / blood
Thromboxane-A Synthase / antagonists & inhibitors*
Valerates / pharmacology*

Substances

Arachidonic Acids
Pentanoic Acids
Prostaglandin Endoperoxides
Pyridines
Receptors, Prostaglandin
Receptors, Thromboxane
Valerates
Arachidonic Acid
Thromboxane A2
Thromboxane-A Synthase
ridogrel