The use of synthetic thromboxane A2 (TXA2-S) and a new class of thromboxane antagonists, indole-2-propanoic acids to characterize the thromboxane receptor

Prog Clin Biol Res. 1989:301:579-83.

Authors

J W Gillard¹, H E Morton, R Fortin, C Yoakim, Y Girard, A Lord, D Ethier, C Leveille, G Letts, J Evans, et al.

Affiliation

¹ Merck Frosst Canada Inc., Kirkland, Quebec.

PMID: 2529557

No abstract available

MeSH terms

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Animals
Binding, Competitive
Blood Platelets / drug effects
Blood Platelets / metabolism
Guinea Pigs
Humans
In Vitro Techniques
Indoles / pharmacology*
Muscle Contraction / drug effects
Platelet Aggregation / drug effects
Propionates / pharmacology*
Prostaglandin Endoperoxides, Synthetic / pharmacology
Receptors, Prostaglandin / metabolism*
Receptors, Thromboxane
Thromboxane A2 / metabolism*
Thromboxane A2 / pharmacology
Thromboxanes / antagonists & inhibitors

Substances

Indoles
Propionates
Prostaglandin Endoperoxides, Synthetic
Receptors, Prostaglandin
Receptors, Thromboxane
Thromboxanes
U 44069
Thromboxane A2
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid