Neuroinflammation mediates synergy between cerebral ischemia and amyloid-β to cause synaptic depression

J Neurosci. 2014 Oct 8;34(41):13571-3. doi: 10.1523/JNEUROSCI.3196-14.2014.

Authors

Walter Swardfager¹, Madelaine Lynch², Sonam Dubey², Paul M Nagy³

Affiliations

¹ Sunnybrook Research Institute, Toronto, Ontario, M4N 3M5 Canada, and Department of Pharmacology and Toxicology, [email protected].
² Sunnybrook Research Institute, Toronto, Ontario, M4N 3M5 Canada, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, M5S 2J7 Canada.
³ Sunnybrook Research Institute, Toronto, Ontario, M4N 3M5 Canada, and.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Amyloid beta-Peptides / pharmacology*
Animals
Brain Ischemia / metabolism*
Entorhinal Cortex / metabolism*
Humans
Male
Microglia / metabolism*
Receptors, Immunologic / metabolism*

Substances

Amyloid beta-Peptides
Receptors, Immunologic

Grants and funding

Canadian Institutes of Health Research/Canada