Vitros 5600 Syphilis TPA assay: evaluation of an automated chemiluminescence assay for detection of Treponema pallidum antibodies in a high prevalence setting

Dorien Van den Bossche; Eric Florence; Christopher Kenyon; Marjan Van Esbroeck

doi:10.1097/OLQ.0000000000000200

Vitros 5600 Syphilis TPA assay: evaluation of an automated chemiluminescence assay for detection of Treponema pallidum antibodies in a high prevalence setting

Sex Transm Dis. 2014 Nov;41(11):680-3. doi: 10.1097/OLQ.0000000000000200.

Authors

Dorien Van den Bossche¹, Eric Florence, Christopher Kenyon, Marjan Van Esbroeck

Affiliation

¹ From the Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

PMID: 25299416
DOI: 10.1097/OLQ.0000000000000200

Abstract

The performance of the Syphilis TPA assay (Ortho-Clinical Diagnostics) on Vitros 5600 Integrated System was evaluated and demonstrated excellent results. Our data support the use of this assay for test confirmation in the traditional algorithm and for screening for syphilis in a routine automated laboratory setting when using the reverse algorithm.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Algorithms
Antibodies, Bacterial / immunology*
Belgium / epidemiology
Clinical Laboratory Techniques*
Female
Humans
Immunoassay*
Luminescent Measurements*
Male
Mass Screening
Prevalence
Sensitivity and Specificity
Sexual Behavior / statistics & numerical data*
Syphilis / diagnosis*
Syphilis / epidemiology
Syphilis / immunology
Treponema pallidum / immunology
Treponema pallidum / isolation & purification*

Substances

Antibodies, Bacterial