Prediction of persistent storage symptoms after transurethral resection of the prostate in patients with benign prostatic enlargement

Urol Int. 2014;93(4):425-30. doi: 10.1159/000357626. Epub 2014 Oct 4.

Abstract

Objective: To identify the prognostic factors causing persistent storage symptoms following transurethral resection of the prostate in patients with benign prostatic enlargement (BPE).

Methods: A total of 116 men with symptomatic BPE requiring surgery were enrolled in the study between January 2011 and December 2012. The patients underwent basic clinical evaluations including transrectal ultrasound, International Prostate Symptom Score and urodynamic study. After 6 months, International Prostate Symptom Score and uroflowmetry were rechecked. The definition of persistent storage symptoms was patients with storage scores >7 points. Logistic regression analysis and receiver operating characteristic analysis were conducted.

Results: The 116 patients were divided into a persistent storage symptom-positive group (n = 33) and a storage symptom-negative group (n = 83). Multivariate analysis showed that the degrees of worse initial storage symptoms (odds ratio [OR] = 8.32), small bladder capacity (OR = 4.31), impaired detrusor contractility (OR = 2.96) and age (OR = 1.05) were consistently associated with persistent storage symptoms.

Conclusions: This short-term study confirms the positive and consistent correlations between the baseline degree of worse initial storage symptoms, bladder capacity, detrusor contractility and age and the improvement in storage symptoms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Area Under Curve
  • Chi-Square Distribution
  • Humans
  • Logistic Models
  • Lower Urinary Tract Symptoms / diagnosis
  • Lower Urinary Tract Symptoms / etiology*
  • Lower Urinary Tract Symptoms / physiopathology
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Prostatic Hyperplasia / complications
  • Prostatic Hyperplasia / diagnosis
  • Prostatic Hyperplasia / surgery*
  • ROC Curve
  • Risk Factors
  • Time Factors
  • Transurethral Resection of Prostate / adverse effects*
  • Treatment Outcome
  • Urinary Bladder / physiopathology*
  • Urinary Bladder Neck Obstruction / diagnosis
  • Urinary Bladder Neck Obstruction / etiology*
  • Urinary Bladder Neck Obstruction / physiopathology
  • Urinary Bladder, Overactive / diagnosis
  • Urinary Bladder, Overactive / etiology*
  • Urinary Bladder, Overactive / physiopathology
  • Urodynamics