Candida parapsilosis osteomyelitis

BMJ Case Rep. 2014 Oct 15:2014:bcr2014206520. doi: 10.1136/bcr-2014-206520.

Abstract

A 51-year-old previously fit and healthy gentleman sustained a circular saw injury to his right thumb with partial amputation and an open multifragmentary fracture of his distal phalanx. He underwent open reduction and internal fixation under the hand surgery team. He developed a postoperative infection discharging pus 2 weeks postoperatively, which later grew Candida parapsilosis. He underwent radical debridement and removal of a K-wire, then a further second debridement 2 days later. Ceftriaxone was started empirically while awaiting cultures. Tissue and bone biopsy samples obtained in theatre all grew C. parapsilosis and he was started on caspofungin for 1 week, and switched on to oral fluconazole to complete a 6-week course. He has progressed well and has regained function in his thumb after 3 months, without any sign of ongoing infection.

Publication types

  • Case Reports

MeSH terms

  • Amputation, Traumatic / surgery
  • Antifungal Agents / therapeutic use
  • Candida
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy
  • Ceftriaxone / therapeutic use
  • Debridement
  • Drug Therapy, Combination
  • Finger Phalanges / injuries*
  • Finger Phalanges / surgery
  • Fluconazole / therapeutic use
  • Fracture Fixation, Internal
  • Fractures, Open / surgery*
  • Humans
  • Male
  • Middle Aged
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / drug therapy
  • Osteomyelitis / microbiology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / microbiology
  • Thumb / injuries*
  • Thumb / surgery

Substances

  • Antifungal Agents
  • Ceftriaxone
  • Fluconazole