Somatic rearrangement of the TP63 gene preceding development of mycosis fungoides with aggressive clinical course

Blood Cancer J. 2014 Oct 17;4(10):e253. doi: 10.1038/bcj.2014.73.

Authors

R N Chavan¹, A G Bridges¹, R A Knudson², R P Ketterling², N Comfere¹, D A Wada³, C Torres-Cabala⁴, D J DiCaudo⁵, G Vasmatzis⁶, M R Pittelkow⁵, A L Feldman²

Affiliations

¹ Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
² Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
³ Department of Dermatology and Huntsman Cancer Center, University of Utah, Salt Lake City, UT, USA.
⁴ Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
⁵ Department of Dermatology, Mayo Clinic, Scottsdale, AZ, USA.
⁶ Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Mutation*
Mycosis Fungoides* / genetics
Mycosis Fungoides* / metabolism
Mycosis Fungoides* / pathology
Skin Neoplasms* / genetics
Skin Neoplasms* / metabolism
Skin Neoplasms* / pathology
Transcription Factors* / genetics
Transcription Factors* / metabolism
Tumor Suppressor Proteins* / genetics
Tumor Suppressor Proteins* / metabolism

Substances

TP63 protein, human
Transcription Factors
Tumor Suppressor Proteins

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