Fluoropyrimidine metabolism in human head and neck cancer xenografts and murine colon tumors

Adv Exp Med Biol. 1989:253B:327-34. doi: 10.1007/978-1-4684-5676-9_48.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Colonic Neoplasms / metabolism*
  • Drug Screening Assays, Antitumor / methods
  • Floxuridine / metabolism*
  • Floxuridine / pharmacokinetics
  • Fluorouracil / metabolism*
  • Fluorouracil / pharmacokinetics
  • Head and Neck Neoplasms / metabolism*
  • Humans
  • Mice
  • Neoplasm Transplantation
  • Orotate Phosphoribosyltransferase / metabolism*
  • Pentosyltransferases / metabolism*
  • Pyrimidine Phosphorylases
  • Tumor Cells, Cultured / metabolism

Substances

  • Floxuridine
  • Pentosyltransferases
  • Pyrimidine Phosphorylases
  • Orotate Phosphoribosyltransferase
  • Fluorouracil
  • doxifluridine