Absolute ethanol embolization of arteriovenous malformations in the periorbital region

Cardiovasc Intervent Radiol. 2015 Jun;38(3):632-41. doi: 10.1007/s00270-014-0993-z. Epub 2014 Oct 24.

Abstract

Objective: Arteriovenous malformations (AVMs) involving the periorbital region are technically challenging clinical entities to manage. The purpose of the present study was to present our initial experience of ethanol embolization in a series of 16 patients with auricular AVMs and assess the outcomes of this treatment.

Methods: Transcatheter arterial embolization and/or direct percutaneous puncture embolization were performed in the 16 patients. Pure or diluted ethanol was manually injected. The follow-up evaluations included physical examination and angiography at 1- to 6-month intervals.

Results: During the 28 ethanol embolization sessions, the amount of ethanol used ranged from 2 to 65 mL. The obliteration of ulceration, hemorrhage, pain, infection, pulsation, and bruit in most of the patients was obtained. The reduction of redness, swelling, and warmth was achieved in all the 16 patients, with down-staging of the Schobinger status for each patient. AVMs were devascularized 100 % in 3 patients, 76-99 % in 7 patients, and 50-75 % in 6 patients, according to the angiographic findings. The most common complications were necrosis and reversible blister. No permanent visual abnormality was found in any of the cases.

Conclusion: Ethanol embolization is efficacious and safe in the treatment of AVMs in the periorbital region and has the potential to be accepted as the primary mode of therapy in the management of these lesions.

MeSH terms

  • Adolescent
  • Adult
  • Arteriovenous Malformations / therapy*
  • Embolization, Therapeutic / methods*
  • Ethanol / administration & dosage*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Orbit / blood supply
  • Orbit / diagnostic imaging*
  • Orbit / pathology*
  • Radiography, Interventional
  • Retrospective Studies
  • Solvents
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Solvents
  • Ethanol