Ovarian Malignancy Probability Score (OMPS) for appropriate referral of adnexal masses

Asian Pac J Cancer Prev. 2014;15(20):8647-50. doi: 10.7314/apjcp.2014.15.20.8647.

Abstract

Background: Ovarian cancer is the most common cancer cause of gynecologic cancer deaths. In order to increase the likelihood of patient survival through primary operation by gyneco-oncologists, an appropriate algorithm for referral is considered here.

Materials and methods: Suspicious adnexal mass cases including ovarian malignancy probability score-1 (OMPS1) scores between 2.3-3.65 are re-evaluated by OMPS2. Sensitivity and specificity of each score were determined.

Results: Sensitivity and specificity with a 3.82 score of OMPS2 in the studied subgroup (OMPS1 scores between 2.3-3.65) were 64% and 76.9% respectively.

Conclusions: Management of OMPS1 scores of below 2.3 with sensitivity of 100% and above 3.65 with specificity of 72.9% is clear. In the subgroup of cases with OMPS1 score between 2.3-3.65, OMPS2 is helpful for triage with a cutoff score of 3.82.

Publication types

  • Comparative Study

MeSH terms

  • Adnexal Diseases / diagnosis
  • Adnexal Diseases / pathology*
  • Adnexal Diseases / surgery
  • Aged
  • Algorithms*
  • Biopsy, Needle
  • Female
  • Humans
  • Immunohistochemistry
  • Iran
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Probability
  • Referral and Consultation / standards*
  • Referral and Consultation / trends
  • Risk Assessment
  • Sensitivity and Specificity
  • Triage