Mechanical thrombectomy for acute stroke in childhood: how much does restricted diffusion matter?

BMJ Case Rep. 2014 Nov 12:2014:bcr2014011465. doi: 10.1136/bcr-2014-011465.

Abstract

Mechanical thrombectomy holds promise for children with large cerebral arterial occlusions, although there are few reports in this population. We report a case of retrievable stent-assisted mechanical thrombectomy in a 5-year-old with basilar artery occlusion, despite late presentation and extensive initial diffusion-weighted imaging (DWI) restriction. This resulted in successful Thrombolysis in Cerebral Infarction 2B reperfusion and excellent clinical outcome. At 6-week follow-up he was completely back to baseline with no residual deficits (pediatric stroke outcome measure=0, modified Rankin scale=0). At 3-month follow-up the patient has not had any recurrent stroke or concern for stroke-like symptoms. We review the literature on mechanical thrombectomy and DWI changes in acute stroke in early to middle childhood (<12 years old).

Keywords: Dissection; MRI; Pediatrics; Stroke; Thrombectomy.

Publication types

  • Case Reports

MeSH terms

  • Basilar Artery / pathology
  • Brain / pathology*
  • Child, Preschool
  • Diffusion Magnetic Resonance Imaging*
  • Humans
  • Magnetic Resonance Angiography
  • Male
  • Mechanical Thrombolysis*
  • Stroke / etiology
  • Stroke / therapy*
  • Vertebrobasilar Insufficiency / diagnosis
  • Vertebrobasilar Insufficiency / therapy*