Protein dynamics: tuning disorder propensity in p53

Nat Chem Biol. 2014 Dec;10(12):987-8. doi: 10.1038/nchembio.1692.

Author

Richard W Kriwacki¹

Affiliation

¹ Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA, and the Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

PMID: 25393491
DOI: 10.1038/nchembio.1692

No abstract available

Publication types

Comment

MeSH terms

Humans
Intrinsically Disordered Proteins / chemistry*
Proto-Oncogene Proteins c-mdm2 / chemistry*
Signal Transduction*
Tumor Suppressor Protein p53 / chemistry*

Substances

Intrinsically Disordered Proteins
Tumor Suppressor Protein p53
MDM2 protein, human
Proto-Oncogene Proteins c-mdm2