Current controversies in prenatal diagnosis 1: NIPT for chromosome abnormalities should be offered to women with low a priori risk

Jan M M Van Lith; Brigitte H W Faas; Diana W Bianchi

doi:10.1002/pd.4530

Current controversies in prenatal diagnosis 1: NIPT for chromosome abnormalities should be offered to women with low a priori risk

Prenat Diagn. 2015 Jan;35(1):8-14. doi: 10.1002/pd.4530.

Authors

Jan M M Van Lith¹, Brigitte H W Faas, Diana W Bianchi

Affiliation

¹ Department of Obstetrics and Fetal Medicine, Leiden University Medical Center, LUMC, Leiden, The Netherlands.

PMID: 25393690
DOI: 10.1002/pd.4530

Abstract

In its successful annual cycle of controversies and debates, the International Society of Prenatal Diagnosis and Therapy once again addressed non-invasive prenatal testing (NIPT) by following up on the 2013 controversy, 'Should non-invasive DNA testing be the standard screening test for Down syndrome in all pregnant women'? with the proposition, 'NIPT for chromosomel abnormalities should be offered to women with low a priori risk'.

MeSH terms

Chromosome Disorders / blood
Chromosome Disorders / diagnosis*
Chromosome Disorders / etiology
Down Syndrome / blood
Down Syndrome / diagnosis
Female
Humans
Infant, Newborn
Pregnancy
Prenatal Diagnosis / methods*
Risk Factors