FeCl3/ZnI2-catalyzed synthesis of benzo[d]imidazo[2,1-b]thiazole through aerobic oxidative cyclization between 2-aminobenzothiazole and ketone

Subhajit Mishra; Kamarul Monir; Shubhanjan Mitra; Alakananda Hajra

doi:10.1021/ol5028893

FeCl3/ZnI2-catalyzed synthesis of benzo[d]imidazo[2,1-b]thiazole through aerobic oxidative cyclization between 2-aminobenzothiazole and ketone

Org Lett. 2014 Dec 5;16(23):6084-7. doi: 10.1021/ol5028893. Epub 2014 Nov 13.

Authors

Subhajit Mishra¹, Kamarul Monir¹, Shubhanjan Mitra¹, Alakananda Hajra¹

Affiliation

¹ Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India.

PMID: 25393913
DOI: 10.1021/ol5028893

Abstract

The FeCl3/ZnI2-catalyzed aerobic oxidative cyclization between 2-aminobenzothiazole and ketone/chalcone for the synthesis of benzo[d]imidazo[2,1-b]thiazole is described. A variety of fused benzoimidazothiazole derivatives are obtained by this protocol.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzothiazoles / chemistry*
Catalysis
Chlorides / chemistry*
Cyclization
Ferric Compounds / chemistry*
Iodides / chemistry*
Ketones / chemistry*
Molecular Structure
Oxidation-Reduction
Thiazoles / chemical synthesis*
Thiazoles / chemistry
Zinc Compounds / chemistry*

Substances

Benzothiazoles
Chlorides
Ferric Compounds
Iodides
Ketones
Thiazoles
Zinc Compounds
aminobenzothiazole compound
zinc iodide
ferric chloride