One of the mainstays of treatment for locally advanced head and neck squamous cell carcinoma is surgery. However, for post-operative patients with high-risk factors for recurrence, surgery alone is insufficient and improving survival requires adjuvant treatment after surgery. Unlike with most other malignancies, the standard adjuvant treatment for post-operative head and neck cancer patients with high-risk factors for recurrence is radiotherapy concurrent with chemotherapy. This review article focuses on the history and future perspectives of adjuvant treatment for post-operative head and neck squamous cell carcinoma.
Keywords: adjuvant treatment; chemoradiotherapy; head and neck cancer; high-risk factors for recurrence.
© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].