Water-soluble nickel-bis(dithiolene) complexes as photothermal agents

Chem Commun (Camb). 2015 Mar 28;51(25):5268-70. doi: 10.1039/c4cc08231a.

Abstract

The remarkable photothermal properties of pegylated nickel-bis(dithiolene) complexes in water can induce cell death under laser irradiation in the near infrared (NIR) region.

MeSH terms

  • Cell Death / drug effects
  • Cell Line, Tumor
  • Dose-Response Relationship, Drug
  • Humans
  • Lasers
  • Low-Level Light Therapy
  • Molecular Structure
  • Nickel / chemistry*
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry
  • Organometallic Compounds / pharmacology*
  • Photochemical Processes / drug effects*
  • Solubility
  • Structure-Activity Relationship
  • Sulfhydryl Compounds / chemistry*
  • Temperature*
  • Water / chemistry*

Substances

  • Organometallic Compounds
  • Sulfhydryl Compounds
  • Water
  • Nickel