Trachelectomy during pregnancy: what has experience taught us?

J Obstet Gynaecol Res. 2015 Apr;41(4):640-5. doi: 10.1111/jog.12594. Epub 2014 Nov 25.

Abstract

The treatment of early stage cervical malignancy in a pregnant patient remains a challenge. We report the successful application of a vaginal radical trachelectomy (VRT) during pregnancy to treat a patient diagnosed with early stage cervical cancer and subsequently review the published work. A 22-year-old female diagnosed at the gestational age of 17 weeks with International Federation of Gynecology and Obstetrics stage IB1 squamous cell cervical carcinoma was treated with VRT at 19(+5) weeks. At 36 weeks, the patient underwent a scheduled cesarean section. A healthy male infant was delivered with a weight of 2795 g. After 13 months of follow-up, the patient is doing well with no evidence of recurrent disease.

Keywords: cervical cancer; fertility; pregnancy; trachelectomy.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Pregnancy
  • Pregnancy Complications, Neoplastic / pathology
  • Pregnancy Complications, Neoplastic / surgery*
  • Pregnancy Outcome
  • Trachelectomy*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / surgery*
  • Young Adult