Molecular epidemiological characterization of uropathogenic escherichia coli from an outpatient urology clinic in rural Japan

Yasuyo D Umene; Lisa K Wong; Tomoya Satoh; Kunikazu Yamane; Mari Matsui; Lee W Riley; Yoshichika Arakawa; Satowa Suzuki

doi:10.1128/JCM.03068-14

Molecular epidemiological characterization of uropathogenic escherichia coli from an outpatient urology clinic in rural Japan

J Clin Microbiol. 2015 Feb;53(2):681-3. doi: 10.1128/JCM.03068-14. Epub 2014 Nov 26.

Authors

Yasuyo D Umene¹, Lisa K Wong², Tomoya Satoh³, Kunikazu Yamane⁴, Mari Matsui⁵, Lee W Riley⁶, Yoshichika Arakawa⁷, Satowa Suzuki⁵

Affiliations

¹ UC Berkeley-UC San Francisco Joint Medical Program, Division of Health and Medical Sciences, School of Public Health, University of California, Berkeley, California, USA [email protected].
² Division of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, California, USA.
³ Satoh Continence Clinic, Saku, Nagano, Japan.
⁴ Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan Department of Public Health, Kawasaki Medical School, Kurashiki, Okayama, Japan.
⁵ Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan.
⁶ Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA.
⁷ Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

Abstract

In the remote Japanese community of Saku, a rural town in the Nagano Prefecture, a large proportion of outpatient urinary tract infections was caused by well-recognized globally dispersed clonal lineages of uropathogenic Escherichia coli (UPEC). However, most of these strains were drug susceptible, suggesting that factors other than selection pressure account for the clonal spread of drug-susceptible UPEC.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Anti-Bacterial Agents / pharmacology
Escherichia coli Infections / epidemiology*
Escherichia coli Infections / microbiology*
Female
Genotype
Humans
Japan / epidemiology
Male
Microbial Sensitivity Tests
Middle Aged
Molecular Epidemiology
Multilocus Sequence Typing
Outpatients
Rural Population
Urinary Tract Infections / epidemiology*
Urinary Tract Infections / microbiology*
Uropathogenic Escherichia coli / drug effects
Uropathogenic Escherichia coli / genetics*
Uropathogenic Escherichia coli / isolation & purification*

Substances

Anti-Bacterial Agents